Analysis of Serum Metabolites to Diagnose Bicuspid Aortic Valve

Analysis of Serum Metabolites to Diagnose Bicuspid Aortic Valve

Bicuspid aortic valve (BAV) is the most common congenital heart disease. The current study aims to construct a diagnostic model based on metabolic profiling as a non-invasive tool for BAV screening. Blood serum samples were prepared from an estimation group and a validation group, each consisting of 30 BAV patients and 20 healthy individuals, and analyzed by liquid chromatography-mass spectrome...

Bicuspid Aortic Valve

Same as Report (SAR) 18. NUMBER

Bicuspid aortic valve disease.

Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media. Changes in the aortic media are present independent of whether the valve is functio...

Bicuspid Aortic Valve

Bicuspid aortic valve (BAV) disease is one of the most frequent observed congenital heart abnormalities affecting 0.5-1.4% of the general population and has a 3:1 male predominance [1-4]. Although some genes have been described that found to be responsible for the abnormal valvulogenesis, little is known about BAV disease with respect to the genetic and embryolog‐ ical insight of calcification ...

Bicuspid Aortic Valve